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MedicineAnatomy and Physiology

Randomized Trial of Neuroprotective Effects of Erythropoietin in Patients Receiving Adjuvant Chemotherapy for Breast Cancer: Position Emission Tomography and NE

Authors: James Abraham; WEST VIRGINIA UNIV RESEARCH CORP MORGANTOWN
Abstract:
Adjuvant treatment with Adriamycin and cyclophosphamide (AC) clearly prolongs the overall survival in women with breast cancer. Cognitive deficits (e.g. problems with memory and concentration) are common during and after adjuvant breast cancer chemotherapy, but the pathophysiology of cognitive phenomens is unknown. The goal of this project is to study the pathophysiology of cognitive dysfunction in patients receiving adjuvant treatment using Positron Emission Tomography (PET) scan.

Limitations: APPROVED FOR PUBLIC RELEASE
Description: Final rept. 1 Oct 2002-31 Aug 2006
Pages: 7
Report Date: SEP 2006
Contract Number: DAMD170210621
Report Number: A192064
Keywords relating to this report:
*BREAST CANCER
*CHEMOTHERAPEUTIC AGENTS
*CHEMOTHERAPY
*CYCLOPHOSPHAMIDE
*PATHOGENESIS
*PATHOPHYSIOLOGY
*POSITRON EMISSION TOMOGRAPHY
BLOOD CIRCULATION
BRAIN
COGNITION
CYTOKINES
ERYTHROPOIETINS
HEMOGLOBIN
MENTAL DISORDERS
NEUROLOGY
PATIENTS
TEST AND EVALUATION
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