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Biological and Theoretical Studies of Adaptive Networks: The Conditioned Response

Authors: John W. Moore; MASSACHUSETTS UNIV AMHERST
 
Abstract: Investigations of adaptive neural networks were conducted using the classically conditioned eyeblink of rabbit, a widely used model system for studies of learning and memory. Our work has focused on processes that mediate adaptive timing of conditioned responses, an important question in the field of learning and motor control. The following experimental projects were conducted: (a) A recording study of the medial geniculate neurons during two-tone differential trace conditioning. (c) A recording study of the ventrolateral pontine reticular formation and pontine nuclei during two-tone differential conditioning. (d) Anatomical experiments using WGA-HRP that clarify cerebellar and red nucleus circuits involved in eyeblink conditioning. (e) Behavioral experiments examining the role of temporal uncertainty in conditioned response timing and topography. (d) Behavioral experiments on asynchronous bilateral eyelid conditioning in rabbits. Adaptive networks, Learning, Computational models, Biological substrates

Limitations: APPROVED FOR PUBLIC RELEASE
Description: Final technical rept. 1 Aug 92-31 Jul 94
Pages: 15
Report Date: 30 AUG 94
Contract Number: F49620-92-J-0387
Report Number: A187482
Keywords relating to this report:
*CONDITIONED RESPONSE
*LEARNING
*MOTOR NEURONS
*NEURAL NETS
BIOLOGY
CIRCUITS
COMPUTATIONS
CONTROL
MODELS
NERVE CELLS
NUCLEI
RABBITS
RETICULAR FORMATION
SUBSTRATES
TOPOGRAPHY
UNCERTAINTY
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