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Biological SciencesBiomedical Instrumentation and Bioengineering

Peptide Nanofilament Engineering

Authors: Alexander Rich; Shuguang Zhang; MASSACHUSETTS INST OF TECH CAMBRIDGE DEPT OF BIOLOGY
 
Abstract: This laboratory studied four systems involving molecular self- assembly during this project period. Each system will open a new avenue of research in developing novel applications for use in biomedical engineering and materials science. These systems include self-assembling oligopeptides that form stable beta sheets in water, peptides that form inter- and intramolecular self- assemblies, peptides that spontaneously assemble onto a surface to form monolayers, and peptides that condense and encapsulate DNA to facilitate highly efficient gene delivery. (2 figures, 12 refs.)

Limitations: APPROVED FOR PUBLIC RELEASE
Description: Final technical rept. 1 Apr 1998-30 Sep 2001
Pages: 10
Report Date: 04 JUL 2003
Contract Number: N00014-98-1-0531
Report Number: A107614
Keywords relating to this report:
*BIOLOGICAL PRODUCTS
*Molecular structure
*MOLECULE MOLECULE INTERACTIONS
*NANOSTRUCTURES
*OLIGOMERS
*PEPTIDES
BIOMEDICINE
ION MOLECULE INTERACTIONS
PROTEINS
RIBONUCLEIC ACIDS
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