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Abstract:
This report presents a Canadian proposal, submitted to ITF-19 of the US/UK/CA Memorandum of Understanding on Chemical and Biological Defensive Materiel, for a biological agent detector which could be fielded by 1995. The proposed system consists of an aerosol particle sizer (APS) and large volume air sampler for non-specific detection and collection/preconcentration. Flow cytometry is used for generic detection. Specific detection is achieved using the advanced concept model (ACM) of the BCD biochemical detector. A Threshold Unit and a standard ELISA immunoassay are used as backups. An alternate system is also proposed if more development time is available beyond the ITF-19 mandate. In it, the standard APS is replaced by one which uses an ultraviolet source to discriminate particles of biological origin from background by fluorescence. Specific detection is achieved by surface plasmon resonance (SPR). The report also describes the results of Canada's original prescreening of technologies, and gives a detailed analysis both of the subtechnologies which comprise the proposed system and of the total system. A description of the current Canadian biodetector, the MASU/MAGIDU, is also given. Expedient, Biological agent detector, Biosensor, Aerosol particle sizer, Surface plasmon resonance, Flow cytometry, Immunoassay, ELISA, Light addressable potentiometry, Air samplers, Collectors, Pre-Concentrators, Non-Specific detectors, Specific detectors, Generic detectors.
| Description: |
Memorandum rept. |
| Pages: |
59 |
| Report Date: |
JAN 93 |
| Report Number: |
A053462 |
Report Unavailable |
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